Wytheville Ramada Inn Wytheville 955 Peppers Ferry Road Wytheville, VA 24382 (276) 228-6000 Map It From the North: I-77 S; Exit 41; Turn right on Pepper's Ferry Rd; Hotel 1/2 block on left side. From the South: I-77 N; Turn at top of exit; Hotel 1/2 block of left. From the East: I-81 S to I-77 N-Exit 72; Exit 41 (First exit on I-77); Turn at top of exit; Hotel 1/2 block on left side. From the West: I-81 N to I-77 – Exit 72; Exit 41 (First exit on I-77); Turn at top of exit; Hotel 1/2 block on left side.